All Matches on Oct 22,2021
| 2. Bundesliga | ||||
| 16:30 | FC Erzgebirge Aue | 1 - 0 | Ingolstadt | AddInfo |
| 16:30 | Paderborn | 1 - 2 | Hamburger SV | AddInfo |
| Bundesliga | ||||
| 18:30 | Mainz 05 | 4 - 1 | Augsburg | AddInfo |
| Eredivisie | ||||
| 18:00 | Willem II | 1 - 1 | Fortuna Sittard | AddInfo |
| Jupiler League | ||||
| 18:00 | VVV | 1 - 2 | De Graafschap | AddInfo |
| 18:00 | Jong FC Utrecht | 2 - 1 | TOP Oss | AddInfo |
| 18:00 | Telstar 1963 | 2 - 2 | Helmond Sport | AddInfo |
| 18:00 | NAC Breda | 3 - 0 | MVV | AddInfo |
| 18:00 | FC Eindhoven | 1 - 3 | Jong Ajax | AddInfo |
| 18:00 | Dordrecht | 3 - 3 | Den Bosch | AddInfo |
| 18:00 | Jong AZ | 0 - 1 | Volendam | AddInfo |
| 18:00 | Almere City FC | 3 - 5 | Jong PSV | AddInfo |
| 18:00 | ADO Den Haag | 0 - 2 | Excelsior | AddInfo |
| Ligue 1 | ||||
| 20:00 | Saint-Étienne | 2 - 2 | Angers | AddInfo |
| Premier League | ||||
| 19:00 | Arsenal | 3 - 1 | Aston Villa | AddInfo |
| Primeira Liga | ||||
| 19:15 | Vitória Guimarães | 2 - 1 | Marítimo | AddInfo |
| Primera División | ||||
| 19:00 | Osasuna | 1 - 1 | Granada | AddInfo |
| RFPL | ||||
| 16:00 | Dinamo Moskva | 4 - 1 | FK Khimki | AddInfo |
| Segunda División | ||||
| 19:00 | Eibar | 2 - 1 | FC Cartagena | AddInfo |
| Serie B | ||||
| 18:30 | US Alessandria Calcio 1912 | 1 - 0 | Crotone | AddInfo |
| Süper Lig | ||||
| 17:00 | Yeni Malatyaspor | 2 - 1 | Altay SK | AddInfo |
Sorry, no matches to display